Source Alagille Syndrome is a rare disease affecting approximately 1 in 30,000 people in the world. There is no known cure for the syndrome.
Grant money will be spent on reagents and services required to do the proposed research, which includes cell culture studies, according to the Sanford Communications team. It uses an advanced method, developed by Sanford researcher Dr. Kyle Roux, to study genetic factors in ALGS patients and relatives. More:Sanford USD Medical Center earns highest certification for stroke care
“This grant helps us continue and broaden our research as we begin to find potential genetic and cellular causes of these kidney diseases,” Kamesh Surendran, PhD and head of the lab said. A primary focus of the lab is to determine the cellular and genetic basis of kidney diseases that occur in patients with a rare disease called Alagille Syndrome. The disease affects multiple organs in the body, including the liver, blood vessels and kidneys.
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