Spacing Pfizer COVID jabs boosts antibody levels: UK study | Coronavirus Pandemic News

Spacing Pfizer COVID jabs boosts antibody levels: UK study |  Coronavirus Pandemic News

“Following two vaccine doses, neutralising antibody levels were twice as high after the longer dosing interval compared with the shorter dosing interval.” “For the longer dosing interval … neutralising antibody levels against the Delta variant were poorly induced after a single dose, and not maintained during the interval before the second dose,” the authors of the study said. Neutralising antibodies are thought to play an important role in immunity against the coronavirus, but are not the whole picture, with T-cells also playing a part.

“But this was at a population level so I think first of all I’d like to say that two doses of Pfizer vaccine are very good at inducing immune responses, and if you’ve had your Pfizer vaccine on a short dosing interval, don’t worry, it’s a great vaccine.” “What we found was, on average, if you had a shorter dosing interval, you had lower antibodies,” Susanna Dunachie, a professor of Infectious Diseases at the University of Oxford and joint chief investigator of the study told Al Jazeera.

The authors emphasised that either dosing schedule produced a strong antibody and T-cell response in the study of 503 healthcare workers. The University of Oxford-led study might help inform vaccination strategies against the Delta variant, which reduces the effectiveness of a first dose of the vaccine even though two doses are still protective, and one author said that the UK’s eight-week gap was a “sweet spot” against Delta.

“We found that the UK strategy – which was to give a longer dosing strategy, which was based on knowledge of vaccines for other diseases, and how a longer gap often is better, and also as a way to quickly jab as many people as possible with one dose – actually ended up giving higher antibody levels,” Dunachie told Al Jazeera. Last December, the UK extended the interval between vaccine doses to 12 weeks, although Pfizer warned there was no evidence to support a move away from a three-week gap. The findings, issued as a preprint, support the view that, while a second dose is needed to provide full protection against Delta, delaying that dose might provide more durable immunity, even if it is at the cost of protection in the short term.

“While we tend to emphasise neutralising antibodies as a measure of the immune response … cellular immunity, which is harder to measure, is also likely to be very important,” said Peter English, former chair of the British Medical Association (BMA) Public Health Medicine Committee. The study found overall T-cell levels were 1.6 times lower with a long gap compared with the short dosing interval of 3-4 weeks, but that a higher proportion were “helper” T-cells, which support long-term immune memory, with the long gap.

The News Highlights

  • Spacing Pfizer COVID jabs boosts antibody levels: UK study | Coronavirus Pandemic News
  • Check the latest Health news updates and information about health.
Disclaimer: If you need to edit or update this news from compsmag then kindly contact us Learn more

For Latest News Follow us on Google News


Latest Headlines
  • Show all
  • Trending News
  • Popular By week
DiaperDash Raises Money, Diapers for Needy Families
DiaperDash Raises Money, Diapers for Needy Families
Collins said they collected more than 14,000 diapers Saturday and raised more than $26,000. She said that money will all go toward buying diapers and baby ...
GLIMPSES: With a phone in hand, Barbados’ Prime Minister phones into UN concerns
GLIMPSES: With a phone in hand, Barbados’ Prime Minister phones into UN concerns
Mottley, who became prime minister of the Caribbean country in 2018, spoke energetically and seemingly off the cuff, delivering vivid lines not replicated in ...
At least 3 killed in Montana Amtrak train derailment
At least 3 killed in Montana Amtrak train derailment
The train had about 141 passengers and 16 crew members onboard, Abrams said. The train had two locomotives and 10 cars, eight of which derailed, he said. “We ...
After 19 months, the Detroit Museum welcomes school trips
After 19 months, the Detroit Museum welcomes school trips
“It is hard to imagine that it has been 19 months since we’ve last heard the sounds of students and teachers exploring the galleries,” said Jason Gillespie, ...
What is the price of Biden’s plan?  Democrats drive to zero
What is the price of Biden’s plan? Democrats drive to zero
Defending a bill not yet fully drafted, Democrats are determined to avoid a deficit financed spending spree. They are growing frustrated by the focus on the ...
Apply for Atlanta Emergency Rental Assistance Money While You Can
China bans encryption once again. Does this mean that e-Yuan is ready for the market?
Chinese regulators tightening the noose around the financial ecosystem is reflective of the ruling party’s concern over control and conceal criminal activity, ...
Norway lifts restrictions on coronavirus after 561 days
Norway lifts restrictions on coronavirus after 561 days
Norway is the latest country in Europe to roll back pandemic-era restrictions. In Sweden, the government confirmed this week that it would proceed with the ...
Fortnite Leaks Map Change Inadvertently
Fortnite Leaks Map Change Inadvertently
More specifically, the video shows a partially destroyed Steamy Stacks. It’s hard to make many conclusions based on the brief snippet of video, but it looks ...
The Tomb Raider studio is assisting Perfect Dark
The Tomb Raider studio is assisting Perfect Dark
The Initiative was formed around 2018 by Microsoft to build big-budget titles for Xbox and PC, and in 2020 at the Game Awards it was finally confirmed that ...
Mum passes away while waiting for a doctor’s appointment on the phone for two hours
Mum passes away while waiting for a doctor’s appointment on the phone for two hours
Relatives of popular baker Helena Maffei, described as the ‘soul of Kidderminster’, say she was trying to get a GP appointment for breathing difficulties ...
Show next
Compsmag - Latest News from tech, business and health
Logo